quinazolinone相关论文
Quinazolinones have emerged as new potential antimicrobial agents because of their broad spectrum of in vitro activity a......
A series of novel quinazolinone benzimidazolyl ethanols with dual-targeting actions were developed and characterized by ......
Poly(ADP-ribose)polymerase(PARP)is a large family of multifunctional enzyme in eukaryotic cells.PARP-1 occupies the larg......
Drug-resistant bacteria pose an urgent public-health crisis.Over the years,β-lactams were the antibiotics of choice for......
Novel Schiff Base-bridged Quinazolinone Imidazoles:Synthesis,Antimicrobial Activity and Supramolecul
A series of novel Schiff base-bridged quinazolinone imidazoles were synthesized and confirmed by NMR and MS spectra.The ......
Synthesis and Their Supramolecular Transportation and Activity of Antimicrobial Quinazolinone Nitroi
Quinolones are one of the most widely prescribed antimicrobial agents as they are generally well tolerated with excellen......
p53 inactivation is a new clinically defined characteristic for cancer treatment-nonresponsive.It is therefore highly de......
Simplification of Rutaecarpine and Luotonin A to tricyclic fused ring and derivatization on ring A f
Rutaecarpine1 and Luotonin A2 are two kinds of natural alkaloids sharing the similar fused quinazolinone structure (Ring......
Synthesis and evaluation of some novel additives as antioxidants and corrosion inhibitors for petrol
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次氯酸根（ClO^-）在人体免疫系统中发挥着重要的作用，其识别与检测备受关注。本文设计合成了一种含有喹唑啉酮骨架的腙型荧光探针（HEMQ），......
目的:探讨一珠二化合物组合化学库结合高通量筛选的方法,为了获得小分子多靶点新型2-喹唑啉酮先导化合物以阻断肺癌的发生及发展进......
摘要以2-氨基-3-甲基苯甲酸为起始原料，经醋酸酐乙酰化、氧化、关环、取代等反应，设计合成了一系列8-羧基-2-甲基-3-芳基（脂肪基）-4（3H）-......
以邻氨基苯甲酸为原料,以不同的中间体和不同的脱水剂对2-甲基-3-甲苯基喹唑啉-4-酮的合成进行研究比较,寻找较佳的合成路径.......
喹唑啉类化合物具有良好生物活性,在农药和医药等领域有着广泛的应用,如杀菌、杀虫、抗炎、抗病毒、抗高血压、抗结核、抗疟、抗肿......
喹唑啉酮及其衍生物是一类具有广泛生物活性的化合物。本文以2,4-二甲基苯胺为起始原料,经乙酰化、氧化、甲酯化、关环、取代等反......
Idelalisib是全球首个高选择性口服磷脂酰肌醇3-激酶delta(PI3K-δ)抑制剂。Idelalisib本身并不能杀死癌细胞,其疗效主要来自于改......
开发了一种(4-(嘧啶-2-基)哌嗪基)(2-苯基喹唑啉)甲酮新的合成工艺,以苯甲酰氯、苯胺等为起始原料,经酰胺化、取代、杂化成环、水......
在离子液体中,邻氨基苯甲酰肼首先和芳酮反应形成腙;在Yb（OTf）3（摩尔比为0.010）催化下,再与另外一分子酮反应,构建一系列不同取代的喹......
Synthesis and Crystal Structure of 2-(4-Oxo-3-o- tolyl-3,4-dihydroquinazolin-2-ylthio)acetohydrazide
The title compound was synthesized from 3-(2-methylphenyl)-2-thioxo-2,3-dihy- droquinazolin-4(1H)-one (4) which was prep......
以邻氨基苯甲酸为母体合成出２－（２－对甲苯磺酰氨基）－４－（３Ｈ）－喹唑啉酮，并对合成方法进行较深入的研究，鉴定出其结构，确定了该物质的一系列光物理参数。......
